Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16
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چکیده
منابع مشابه
Two pericentric inversions of human chromosome 11.
A pericentric inv(11) (pl5q23) detectable by G-, Q-, and R-banding and occuring in 1 member of each of 3 generations of a family is described. In another family studied by several banding methods in search of chromosomal markers, a pericentric inv(11) (p11q11) was found. It was detectable only by C-banding, the darkly staining band being located on the short-arm side of the centromere. The reas...
متن کاملBreakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes).
The study of breakpoints that occurred during primate evolution promises to yield valuable insights into the mechanisms underlying chromosome rearrangements in both evolution and pathology. Karyotypic differences between humans and chimpanzees include nine pericentric inversions, which may have potentiated the parapatric speciation of hominids and chimpanzees 5-6 million years ago. Detailed ana...
متن کاملIntrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms.
Amplicons--large, nearly identical repeats in direct or inverted orientation--are abundant in the male-specific region of the human Y chromosome (MSY) and provide targets for intrachromosomal non-allelic homologous recombination (NAHR). Thus far, NAHR events resulting in deletions, duplications, inversions, or isodicentric chromosomes have been reported only for amplicon pairs located exclusive...
متن کاملComparative mapping of the cri du chat and DiGeorge syndrome regions in the great apes.
Structural variations between great ape and human chromosomes due to pericentric inversions and translocations have created at apparent controversy during the reconstruction of hominoid phylogeny. One such variation involves human chromosome 5, which is equivalent to chromosome 4 in chimpanzee and orangutan but equivalent to segments of chromosomes 4 and 19 in gorilla. Obviously, neither bandin...
متن کاملRecombination Between Existing Homologous Chromosomes
Enchanced survival of ultraviolet-irradiated Escherichia coli dependent upon the recA + gene appears to result from the ability to seal gaps in newly synthesized deoxyribonucleic acid (DNA) produced when DNA containing pyrimidine dimers is replicated (8). Strains which are recombination-deficient (recA) do not seal these gaps and degrade their DNA to a considerable extent. Rupp and Howard-Fland...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2005
ISSN: 1088-9051
DOI: 10.1101/gr.3732505